Metal-Organic Frameworks as Host for Encapsulation of Enzymes


Metal-Organic Frameworks as Host for Encapsulation of Enzymes

Bhagwati Sharma, Tridib K. Sarma

Enzymes are a class of highly selective and efficient natural catalysts. The use of enzymes for catalysis often requires them to be immobilized onto solid supports so that they can be efficiently recycled, the contamination due to presence of enzymes in the product can be minimized and their application in biomedicine can be explored. Various strategies for the use of metal-organic frameworks (MOFs) as host material for the encapsulation of enzymes have been discussed. Recent developments on the preparative strategies and applications of MOF encapsulated enzyme with special focus on catalysis are summarized in this chapter. The enhancement/retention of enzymatic activity of the composite material compared to free enzymes in denaturation conditions and advantages of encapsulation of the enzymes has been reviewed.

Enzymes, Metal-Organic Frameworks, Encapsulation, Catalyst, Reusability

Published online 6/30/2019, 20 pages

Citation: Bhagwati Sharma, Tridib K. Sarma, Metal-Organic Frameworks as Host for Encapsulation of Enzymes, Materials Research Foundations, Vol. 53, pp 215-234, 2019


Part of the book on Metal-Organic Framework Composites

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