LPBF process of Zn-modified NiTi alloy with enhanced antibacterial response
Carlo Alberto Biffi, Jacopo Fiocchi, Francesca Sisto, Chiara Bregoli, Ausonio Tuissidownload PDF
Abstract. In this work the use of Laser Powder Bed Fusion (LPBF) process enabled the development of customized implants with advanced functional materials for the biomedical sector. In details, Ni rich NiTi Shape Memory Alloy (SMA) powder, mixed with Zn powder, were used for building samples, able to couple the typical superelasticity of the initial material with the antibacterial response, offered by the dopant element. The main parameters of the LPBF process were revised for achieving full dense parts. Further, the functional performances of the novel NiTiZn SMA were analyzed and compared with the ones of the reference material. Finally, the antibacterial response against different bacteria was tested. It was found a promising antibacterial response against Staphylococcus aureus of the NiTiZn SMA, while the addition of Zn into NiTi did not supress the martensitic transformation of the NiTi alloy and allowed to maintain the superelastic recovery.
Additive Manufacturing, Laser Processes, Shape Memory Alloy
Published online 9/5/2023, 8 pages
Copyright © 2023 by the author(s)
Published under license by Materials Research Forum LLC., Millersville PA, USA
Citation: Carlo Alberto Biffi, Jacopo Fiocchi, Francesca Sisto, Chiara Bregoli, Ausonio Tuissi, LPBF process of Zn-modified NiTi alloy with enhanced antibacterial response, Materials Research Proceedings, Vol. 35, pp 127-134, 2023
The article was published as article 16 of the book Italian Manufacturing Association Conference
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 Funakubo, H.: Shape Memory Alloys, Gordon and Breach Science Publishers, Amsterdam, (1987).
 S.A. Shabalovskaya, Biomed. Mater. Eng. 12 (2002) 69-109.
 J.X. Xiong,, Y.C. Li, X.J. Wang, P.D. Hodgson, C.E. Wen, J. Mech. Behav. Biomed. Mater. I (2008) 269-273. https://doi.org/10.1016/j.jmbbm.2007.09.003
 S. Thomas, Y. Grohens, N. Ninan, in: A.R. Unnithan, R.S. Arathyram, C.S. Kim (Eds.), Scaffolds With Antibacterial Properties, Elsevier Inc., New York (2015), pp. 103-120. https://doi.org/10.1016/B978-0-323-32889-0.00007-8
 Erlin Zhang, Xiaotong Zhao, Jiali Hu, Ruoxian Wang, Shan Fu, Gaowu Qin,Antibacterial metals and alloys for potential biomedical implants,Bioactive Materials,Volume 6, Issue 8,2021,2569-2612. https://doi.org/10.1016/j.bioactmat.2021.01.030
 M. Saugo, D.O. Flamini, L.I. Brugnoni, S.B. Saidman, Silver deposition on polypyrrole films electrosynthesised onto Nitinol alloy. Corrosion protection and antibacterial activity, Materials Science and Engineering: C, Volume 56, 2015, 95-103, ISSN 0928-4931, https://doi.org/10.1016/j.msec.2015.06.014
 Yongkui Yin, Ying Li, Xu Zhao, Wei Cai, Jiehe Sui, One-step fabrication of Ag@Polydopamine film modified NiTi alloy with strong antibacterial property and enhanced anticorrosion performance, Surface and Coatings Technology, Volume 380, 2019, 125013, ISSN 0257-8972. https://doi.org/10.1016/j.surfcoat.2019.125013
 Pipattanachat, S., Qin, J., Rokaya, D. et al. Biofilm inhibition and bactericidal activity of NiTi alloy coated with graphene oxide/silver nanoparticles via electrophoretic deposition. Sci Rep 11, 14008 (2021). https://doi.org/10.1038/s41598-021-92340-7
 J. Ye, B. Li, M. Li, Y. Zheng, S. Wu, Y. Han, Acta Biomater 107 (2020) 313-324. https://doi.org/10.1016/j.actbio.2020.02.036
 K. Yusa, O. Yamamoto, M. Iino, H. Takano, M. Fukuda, Z. Qiao, T. Sugiyama, Arch. Oral Biol. 71 (2016) 162-169. https://doi.org/10.1016/j.archoralbio.2016.07.010
 Bassani, P.; Fiocchi, J.; Tuissi, A.; Biffi, C.A. Investigation of the Effect of Laser Fluence on Microstructure and Martensitic Transformation for Realizing Functionally Graded NiTi Shape Memory Alloy via Laser Powder Bed Fusion. Appl. Sci. 2023, 13, 882. https://doi.org/10.3390/app13020882
 Farber, E., Zhu, J. N., Popovich, A., & Popovich, V. (2020). A review of NiTi shape memory alloy as a smart material produced by additive manufacturing. Materials Today: Proceedings, 30, 761-767. https://doi.org/10.1016/j.matpr.2020.01.563
 Safaei, K., Abedi, H., Nematollahi, M., Kordizadeh, F., Dabbaghi, H., Bayati, P., Reza Javanbakht, Ahmadreza Jahadakbar, Mohammad Elahinia Poorganji, B. (2021). Additive manufacturing of NiTi shape memory alloy for biomedical applications: review of the LPBF process ecosystem. Jom, 73, pages3771-3786 (2021). https://doi.org/10.1007/s11837-021-04937-y
 A.G. Demir, P. Colombo, B. Previtali, From pulsed to continuous wave emission in SLM with contemporary fiber laser sources: effect of temporal and spatial pulse overlap in part quality, Int. J. Adv. Manuf. Technol. (2017) 1-14. https://doi.org/10.1007/s00170-016-9948-7
 Mahalakshmi S, Hema N, Vijaya P.P., In Vitro Biocompatibility and Antimicrobial activities of Zinc Oxide Nanoparticles (ZnO NPs) Prepared by Chemical and Green Synthetic Route- A Comparative Study. BioNanoScience (2020) 10:112-121 https://doi.org/10.1007/s12668-019-00698-w
 ASTM E2180-07 (2012): Test method for evaluation of the activity of antimicrobial agent in polymeric or hydrophobic material.
 Biffi, C. A., Fiocchi, J., Sisto, F., Bregoli, C., & Tuissi, A. (2023). Enhanced antibacterial response in Zn-modified additively manufactured NiTi alloy. Materials Letters, 335, 133749. https://doi.org/10.1016/j.matlet.2022.133749