Separation and Purification of Bioactive Molecules by Ion Exchange


Separation and Purification of Bioactive Molecules by Ion Exchange

Rabiul Alam, Bidyut Saha

Bioactive molecules (or signaling molecules) are involved in tissue regeneration and have an important role in modulating the microenvironment in vivo. Bioactive chemicals have the ability to govern host cell motility, proliferation, and differentiation, as well as enabling cells to interact with their surrounding microenvironment via particular receptors for chemical recognition. This chapter introduces ion-exchange chromatography (IEC) as a method for separating and purifying bioactive compounds such as polyphenols, catechin derivatives from complicated plant mixtures, proteins, minor whey protein, peptides, human C-peptide, alkaloids from Chinese medicines, plasmid DNA and carbohydrates.

Ion-Exchange Chromatography, Biochemical Purification, Bioactive Molecules, Polyphenols, Catechin, Proteins, Peptides, Human C-Peptide, Alkaloids, Plasmid DNA, Carbohydrates

Published online 12/20/2022, 18 pages

Citation: Rabiul Alam, Bidyut Saha, Separation and Purification of Bioactive Molecules by Ion Exchange, Materials Research Foundations, Vol. 137, pp 75-92, 2023


Part of the book on Ion Exchange Resins

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