Hybrid Materials based on Silica Nanostructures for Biomedical Scaffolds (Bone Regeneration) and Drug Delivery


Hybrid Materials based on Silica Nanostructures for Biomedical Scaffolds (Bone Regeneration) and Drug Delivery

Mojdeh Rahnama Ghahfarokhi, Jhaleh Amirian

Silica nanoparticles with nanoporous nature are introduced as thermally and chemically stable nanomaterials with controllable porosity and morphology. The nanoparticles can be divided into three groups: microporous, mesoporous, and macroporous based on the porous size. The use of these materials for different applications is associated with their unique properties as disinfectants. This chapter discusses different synthesis methodologies to prepare well-dispersed mesoporous silica nanoparticles (MSNs) and hollow silica nanoparticles (HSNs) with tunable dimensions ranging from a few to hundreds of nanometers of different mesostructures. Several good characteristics of the MSNs, best biocompatibility and low toxicity, are proposed as the basis of the carrier for the controlled release of drugs, genes into living cells and bone regeneration.

Silica, Sol-gel, Mesoporous, Biomedical Applications, Drug Delivery

Published online 11/20/2020, 18 pages

Citation: Mojdeh Rahnama Ghahfarokhi, Jhaleh Amirian, Hybrid Materials based on Silica Nanostructures for Biomedical Scaffolds (Bone Regeneration) and Drug Delivery, Materials Research Foundations, Vol. 87, pp 103-120, 2021

DOI: https://doi.org/10.21741/9781644901076-4

Part of the book on Nanohybrids

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